On Les Paul types with 4 pots I pick the middle and blend. I start on 10 with the volumes knobs. Turning down slightly on either will give me either full neck or bridge. From there I turn down both to 8 or 9 and blend in what I want more of.
Strats: It’s usually position 4, middle and neck. None of the knobs are on 10. If I wank over that I turn on a klon fake.
If I’m using a Fuzzface type pedal then all the above goes out the window because it doesn’t apply if I’m trying to get that Spirit in the Sky thing. I do this 3rd Stone from the Sun thing too on the A string while droning the E string using a strat or a P90 P guitar. It’s a take off of what Gary Clark Jr does on the Black and Blue album but I’m not using a band so it’s both the bass and guitar parts to make it more full. Doesn’t work with humbuckers or EMG type pickups. It’s not automatic either, like plug it together stomp the pedal and there it is. I do this run up to it where I’m basically the using same notes I use in 3SftS but randomly with some short single note runs while adjusting volume and tone. If I don’t find the spot the droning E string just swallows up any single note expression. When I find it I do a slide into the first note of 3SftS and if you know the song then you instantly know that where it’s going. Hit the looper, run through it a couple times, start the loop and blaze off into some fuzz spitting ejaculation goodness. That’s in the bridge position. Have to be mindful of the volume control because if I’m not playing it’s buzzing like a hornets nest out of control and feeding back.
I guess I don’t really sit in one spot.